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Bu and MGE cell transplantation alone or in combination therapy promoted neural repair and reduced glial scar formation in mice with SCI. (A–D) IF staining of GFAP, <t>NF200,</t> MBP and Tuj1 in spinal cord tissue at 28 days post-treatment; (E–H) Semi-quantitative analysis of GFAP, NF200, MBP and Tuj1 expression in spinal cord tissue at 28 days post-treatment (n = 3). Scale bar: 50 μm. The data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
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Bu and MGE cell transplantation alone or in combination therapy promoted neural repair and reduced glial scar formation in mice with SCI. (A–D) IF staining of GFAP, <t>NF200,</t> MBP and Tuj1 in spinal cord tissue at 28 days post-treatment; (E–H) Semi-quantitative analysis of GFAP, NF200, MBP and Tuj1 expression in spinal cord tissue at 28 days post-treatment (n = 3). Scale bar: 50 μm. The data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
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Bu and MGE cell transplantation alone or in combination therapy promoted neural repair and reduced glial scar formation in mice with SCI. (A–D) IF staining of GFAP, <t>NF200,</t> MBP and Tuj1 in spinal cord tissue at 28 days post-treatment; (E–H) Semi-quantitative analysis of GFAP, NF200, MBP and Tuj1 expression in spinal cord tissue at 28 days post-treatment (n = 3). Scale bar: 50 μm. The data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.
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Bu and MGE cell transplantation alone or in combination therapy promoted neural repair and reduced glial scar formation in mice with SCI. (A–D) IF staining of GFAP, NF200, MBP and Tuj1 in spinal cord tissue at 28 days post-treatment; (E–H) Semi-quantitative analysis of GFAP, NF200, MBP and Tuj1 expression in spinal cord tissue at 28 days post-treatment (n = 3). Scale bar: 50 μm. The data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Journal: Frontiers in Immunology

Article Title: Combined use of Bumetanide and MGE cell transplantation alleviates neuropathic pain and its mechanism after spinal cord injury in mice

doi: 10.3389/fimmu.2026.1751436

Figure Lengend Snippet: Bu and MGE cell transplantation alone or in combination therapy promoted neural repair and reduced glial scar formation in mice with SCI. (A–D) IF staining of GFAP, NF200, MBP and Tuj1 in spinal cord tissue at 28 days post-treatment; (E–H) Semi-quantitative analysis of GFAP, NF200, MBP and Tuj1 expression in spinal cord tissue at 28 days post-treatment (n = 3). Scale bar: 50 μm. The data are presented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.

Article Snippet: NF200 , Rabbit , 1:200 , 18934-1-AP , Proteintech , IF.

Techniques: Transplantation Assay, Staining, Expressing